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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13291d89b3f2993592a57f5a3b1c2fbfea8f00e4cd5d46d822e1a11485533b75' 
  AND token = 'KQSLsHJO3iBrlGONDU3jrrdNa1hb1QgXS4c44EMJMxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}