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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '922c4a23edbcc59b435eec60fccf8ff3881ccee7b7b3a7745b0e648a9038260c' 
  AND token = '75oxxuhj/2S74wlKm3LskSi4csnAawVWeBdwM5mKTQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}