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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '146e3a10dead74a126c2a0d6c1d504bacb4042b8df6be7873eb7cd2f3ba239af' 
  AND token = 'tyebi4b1sAxS6L0eAXAor5ARkBykYAhmdgr2z483QKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}