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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5d955e1c49266f82b9e6f9f1cdc7a1538acf32b86130a3f28e756e30677e111' 
  AND token = 'fdwHgR3RGNrEQGXGjx35DR39cx8jCbJ4nJwlrWD8iCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}