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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3df10dc97719ad86789da4a54b2c8b2a9773197fd1169aeb91458a29e9d067' 
  AND token = 'KX/b/JKEfPU8wTWteuYE0/h3l6PME3AVeGPeSpf5CAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}