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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8183cfd45a9c0dae66f152355180ad22095129457b15bbcab030f7add2bd350' 
  AND token = 'Qf/nUxxnnA1wWVf6SQZGMz6G+cTeNNCJeLxM5VI4HG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}