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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34621ffbd8abe188ec01805e5a7504fab7ad394044335b930763e98f97eb559e' 
  AND token = 't5yQ7MWW+3eO/7pfqbOfmr18dbhjMHagGqTIakbMXUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}