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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '574140aa619223bb33454bce88b311c4d99c48b408eaaacf4e54974bd2424c71' 
  AND token = 'fz/hWdsctUy2pdFzLxDUWo6V/mptdpLmefC7AH2NH7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}