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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca0403ff241bc8df10757d52f6e10aec392802bce38367d7e9d7c1feec15abc' 
  AND token = 'Rb6MtVE2USfVlRO2uCC0vbs1XmO/AiQwNfWv5IKAgzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}