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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2cdf1e18f9fb8883a2dfb791870153b56d01219808c0ac4419265180d99d654' 
  AND token = 'LhsJ/P8IxCKfIc0MowoM0ZkqC6f7+ekCVii2yMIZIXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}