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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b0758101d0afaab6238fa0f59684a78916f6147fe4ecacbb39b72832f030f20' 
  AND token = 'UX+QWX8zkh9f7CBwHDol4oCT3h83GkdtA1CkjXfL6pY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}