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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b681b01f8083145590f746390a21247433b0dc26b9e1147937873d723611b4' 
  AND token = 'vFCs0p0gyOv+v5VGzghgOqUY21z2CEzNPMg4xzeiW3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}