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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b75f1d70a9277c2266640ca622799223a4c810cfb02685e7db2bb0cd645ed4c' 
  AND token = 'JeJz9LY9kTnpSrB3JQPGBPwXzD7y7ujH1bRykOr5aso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}