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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f1c0aef21e593ca4c94baf35d0396e2edae2d9847644eca65583fbba2e4902' 
  AND token = 'yp5FNz8/O0UvqfJUa1LhPlT015kkWfmd0wpappIwa8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}