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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aaf1337196d2d3eff41edba03d168040e1098fac8724463897d276dc6aafcc8' 
  AND token = 'pD9qKvr8C1xmMWqF+BP0pYHGfsVZYTzF8nCofl0YMWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}