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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b142d54071c42efb80ced3511eac0dbd23d394523fb0d4d70b45b0e5bb52195' 
  AND token = 'a1RvS/ckSKnebIYCbM7SVEgCxJMbrPCCsDr8e5mpQzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}