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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef7493bcc27db766253dedcdabc8dddcb1649b3c7643fd5d2b2d92e8a54bc7a7' 
  AND token = 'm/CyqyWp8oq+7jTOFuGlgKe5OPAZkFVaSo736kQBsAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}