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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d9140cd40b1221658e6922c10fba05f0f87cbb964ac43c40bddd016267e4df' 
  AND token = '0/AZpwoHhgPlWPw+LHO5V+HLNQO8R7FpAnnX60+iIFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}