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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63f73d03df00cf8d2e304a53f25313e62cb93bd90ce0ba092a57c53ed3234744' 
  AND token = 'vj7Ej+Jj7NKN9mcgyj470j4c/xZTCTnjf0jP7sUlvWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}