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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bd9158836c90ebce205689675a1e5a079e197589259a05f32962e4c97ca8df7' 
  AND token = '+MVMTsnLDi5PWDMs/5UDEUrRBzyHET1EUytk5dNl0Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}