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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '346a1fd535ba87ee9e63e9895a785c8860657df130e0ec1dda6c5db9cdb63f4f' 
  AND token = 'eVUTAVhBc59bRd0N5VypKqtJLSgh6CGPt/H9MsTHRuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}