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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049817f5270fd34e395cc5592d730afd68d65c9a4ae3099446c5e7a2bed46191' 
  AND token = '02D+wQK+Qyx3rGWNsC8trIP9L6vbv0B4ZeabPVpH+LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}