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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fec8868cf7cf31a37c710098018230a6705e433aa2189b9a7aac81d3bdd50db' 
  AND token = '7Z+qtDTMEo/FLcqwK/UcT8Ak9nq6hpkZ0ayZVFHim8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}