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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48ad2d27b02c63331dad44f4834154012f4ddb922199f8d2d3f4fee672a5361' 
  AND token = '4TOl9lOMRZ/fcGqyS3DHI8wYuVW4uMVggNSc1hE5aeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}