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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd9233661d33f0f9d335097f83ed00f2b5b6728e327cba6ee71e751204401025' 
  AND token = 'VKoU6nXXI3692SxSHK+KBgnGmD5kctFxd3l/YFKdnLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}