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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06f579289a4cceee046b62eb20dfb2d32330af5cb78f548b4cd472ddf48ec1f3' 
  AND token = '6TZxwYvzN/od7mPKAyPm9rEW4MfwiYUOSb5M43MXrcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}