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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c85303582ac4de083af48b0c45fd8efe8abb2b595f37a45600bcc368f4a81fdb' 
  AND token = 'P5fDwo6/XfilwnSx4RTdcpjwgwvQZrt9aHehnZuhgbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}