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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce7205a861558d1a5d84366af2be4c66c3e1811d6d59368c1770997c990ff320' 
  AND token = 'Oxk+kk1Tk/zXEXqfz8S/vpYBrA1p0D5UFzJdY+PuH8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}