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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2154f6053effad505fe052333d6b8824b334241d46b11b9a9f90eca247a3aa' 
  AND token = '57N3h1K0sWBw32xMfX0NV62Ko7wvoHkRY+Cz0RfnLiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}