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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09de5a31608766a72eda93ca640daf3dcfe3a6b117eb1c5e7d5f717a1532f610' 
  AND token = 'ydVGtT9WSD3kUQY0Tv5RtGIohLB3IExBeoH8DR1cPTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}