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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e539a6fa3a54574f97db6aecbe2a4623a0480ad1510e01fd0f08eb8994faf9' 
  AND token = 'J59sZHhyHudupF5LGAu4jYRxwDOU401Cx5H5MT1ZqYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}