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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28125b9849a22bc52a7f2617d62d854851fca283ed90bea8fadcb18128616a1a' 
  AND token = 'PUVAufFV4d/4ucAWKgLBRDFSMHoKxISIKX3s/Si6WJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}