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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd3e45d5a3b0d397f40728cc42b3008fdfd343b87c57a91a474abd2c4a4d3ec' 
  AND token = 'NgaOtrD0SX9AHNwGDVWrCRazw+hlnZgy/YIK2crW5DI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}