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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256c039b75daf3dca428c0b0ce85c3f1b374913cc4960edcb67348c9aa811a2a' 
  AND token = 'T9/IlHVUjBY1jaAYVhouDSoZqF0MEwZnkTeTzxRcX7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}