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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a67e9a03b148152076651045491d222bb4342244951883bfd337220abb3530' 
  AND token = 'auRVh55s+9mOl1lz4ZNm5opJjTdX7GPlDPSODJfLyXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}