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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151288774c55b6016a5fe2a88040ea3a850282151b22fe889d5474f610bb1fab' 
  AND token = '5DkHQfyzN+OuNnmToACJ2m9N0Kr5vmAi8WgxNqD9TlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}