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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73534c118288a85fc54b238e05789fc9ebc4cf4c71add5289bfbb01a33d36c32' 
  AND token = '2HKbWYkLwcCc49DNRuURUj3JkFTmGExq+Z0io0uCj40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}