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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9e8df8bde995909945eb8f45e0bab2a1fed3b9584f6e3d0cc314c65df48809f' 
  AND token = 'VPmbyFl24JZkB4i2F/+KYaydbrX7uejEW2fjMgie3CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}