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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b781263e1514960d3b86ec55b8a8381911ad91ebe5918b5be22413c0a620c1e2' 
  AND token = 'KrwQO8wKUvOw5itFLV8Vu+3iSQAbvAjAfq0HEeTaT3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}