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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c846ab24a32469a055875e200d70d8f2cb2636b58f8fa8f58a526bfa1f478ac0' 
  AND token = 't11sTi5Q1KODOkfvBbPoyHRJGSJOlyBfPHbA1VeK0n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}