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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a8c241d37fe8a7a53cfcfc317382a4a8210e7ce6f6fc73e5b4dbd3bc7948bcf' 
  AND token = 'YoNBngsyeSX0cUFBodiE+aJXZoxUYb1YsgbRvkN0xPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}