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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f4d62b63729fa3f3ca857da46086817eaff6cb41df0954395ed1e410a9fbfa' 
  AND token = 't4ncXKb5qvk75VPwGLCCt50ESBUdfTMdgacEMcRHrTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}