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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ca8b90e347463aa774d55b9256d7be31d6d34eda67b70fd350f979602723be1' 
  AND token = '/bED+mDLxW2OrFKnO1smE8PchRchGqU13fbkDZKXnwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}