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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aca6f9f4122caac25df3db9261f70d4e744db8c98c6241d30f5ccd960b425018' 
  AND token = 'C9b0zhsbXE2OFHA3PowFZREWp8yMlAxhlILkR63O5PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}