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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0fab0851d1927d807e57de6e4dfb613fd3747e2d771f253b4960260002d1f3' 
  AND token = 'HICdcD0m1ywy+4ni4NGD7QvYGl/syxD3o59vSTw9OmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}