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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e84ab6a0dad4febd0157a7f3af9838b544f8a7004253812f823bb3d3d9344f3' 
  AND token = '4+JDLsflWaKr9t2XGM6s0LYRmIwmFk3yWo3QDLv7aU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}