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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e65d990abb7400e40021effd82f839ef1c34399f75e8c59f3df9355ff48e16a' 
  AND token = '0ca3Adz6JiqDpcdpmpWwzwaCiO8qYc5i7GLEh5H7nEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}