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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721ab5b67f208e93ee361409ba195f7b02c6599cdd620d886d8757f1e836a7b8' 
  AND token = '8HCe2COeaejhNSre8WxV6/Cibjsa75KXvBHmUv7Yf/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}