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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c76b57110db827b3ae04c049b3bb33b0019113bb5b13be293dde3b5dd627559' 
  AND token = 'WZ2xdmvr06ALr+JJ9K5vEB1Ukz2O9tDSeRTclhZjERs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}