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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e66570e850914696d6359ff9ec04079cad7c3c450131d3c2c7a73027ad6864b' 
  AND token = '/FXkHY3iEE2QKNnB1RiCjnlUilDqWSJPDfKNk4pAWOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}